Which of the following statements are correct?

(I) Inorganic chemicals are present mostly in aqueous phase while organic in both, aqueous and non-aqueous. Cellular pool comprises of both crystelloid and colloidal particles.

(II) Water is universal solvent, as it can dissolve both polar and non-polar solutes, it has high boiling point due to hydrogen bonding.

(III) Some proteins are an assembly of more than one polypeptide. The manner in which these individual subunits arrange forms the architecture of protein.

(IV) In protein tertiary structure, the coils and folds are so arranged as to hide polar side chains inside and expose the non-polar side chains.

(V) The conformation of protein is easily changed by , temperature and chemical substances and hence, its function is labile and subject to regulation.
Choose the correct answer from the options given below.