Home Chemistry NEET Full Syllabus Mock Test 180 Question New Syllabus Mock Test - 15 PCB Which of the following approaches or methods…
Chemistry NEET Full Syllabus Mock Test 180 Question New Syllabus Mock Test - 15 PCB Single Correct MCQ
Published on: August 13, 2026

Which of the following approaches or methods is not used for sequencing the human genome?

A
Identifying all the genes that are expressed as RNA
B
Simply sequencing the whole genome, which contains all coding and non-coding sequences, and later assigning different regions in the sequence with functions
C
Isolating the entire DNA content from the nucleus and running it for sequencing in a single run using automated DNA sequencers worked on the principal of Sanger's method.
D
Total DNA from a cell is isolated and converted into random fragments, which are then cloned in a suitable host using specialized vectors

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The correct answer is:
C

DNA is a very long polymer, and there are technical limitations in sequencing very long pieces of DNA. Thus, it is not possible to sequence the entire nuclear DNA in a single run.

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