Hardy-Weinberg principle comes from considering what happens when Mendelian genes act on populations. The model predicts that there will be no change in allele frequencies when
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• The Hardy-Weinberg principle states that allele and genotype frequencies in a population remain constant from generation to generation if no evolutionary forces are acting and if mating is random.
• Migration (gene flow) changes allele frequencies, so this violates Hardy Weinberg equilibrium.
• A bottleneck reduces population size drastically, causing genetic drift and changing allele frequencies.
• Mutation and, natural selection alter allele frequencies, so this breaks equilibrium.
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