Refer to the following figure for mechanism of hormone action.
Which of the following set of hormones show the given mechanism of action?
Text Solution
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• Lipid-soluble hormone diffuses through the cell membrane.
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• Binds to an intracellular receptor.
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• Forms a hormone-receptor complex.
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• Complex binds to genome → activates transcription → mRNA → proteins.
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• Leads to physiological responses (e.g., tissue growth, differentiation).
• This mechanism is typical of steroid hormones (like estrogen, progesterone, cortisol, aldosterone) and also thyroid hormones (though they are amino acid-derived, they act like steroids because they are lipid soluble).
• Oestrogen and progesterone are steroid hormones which act via intracellular receptors.
• Insulin and glucagon : membrane bound receptors
• Thyroxine : acts intracellularly
• FSH: acts via membrane bound receptor
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