Pyruvate, which is formed by the glycolytic catabolism of carbohydrates in the cytosol after it enters the mitochondrial matrix undergoes oxidative decarboxylation by a complex set of reactions catalysed by pyruvate dehydrogenase.
The scheme of glycolysis was given by Gustav Embden, Otto Meyrhof, and J.Parnas and is often referred to as the EMP pathway.
In the electron transport system, the energy of oxidationreduction is utilised for the production of proton gradient required for phosphorylation; thus, this process is also called oxidative phosphorylation.
The TCA (tricarboxylic acid cycle) starts with the condensation of the acetyl group with oxaloacetic acid (OAA) and water to yield citric acid. The reaction is catalysed by the enzyme citrate synthase. Thus, Option is correct.