Nicotine, an I stimulates II gland to release adren ne and nor-adren ne into blood circulation, both of which III blood pressure and increase heart rate. Smoking is associated with increased incidence of cancers of lung, urinary bladder and throat, bronchitis, emphysema, coronary heart disease, gastric ulcer, etc. Tobacco chewing is associated with increased risk of cancer of the oral cavity. Smoking increases IV content in blood and reduces the concentration of haembound V
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