Following are the steps in one type of gene therapy –
(I) Inject engineered cells into patients bone marrow
(II) Viral DNA earring the normal allele inserts into chromosome
(III) Let retrovirus infect bone marrow cells that have removed from patient and cultured
(IV) Insert RNA version of normal allele into retrovirus
Which of the following is correct sequence of steps –
Text Solution
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The correct sequence of steps in this type of gene therapy is:
(IV) – Insert RNA version of the normal allele into a retrovirus.
(III) – Let the retrovirus infect cultured bone marrow cells removed from the patient.
(II) – Viral DNA carrying the normal allele integrates into the chromosome of the patient's cells.
(I) – Inject the genetically engineered cells back into the patient’s bone marrow.
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