The sequence of transmission of an impulse at chemical synapse begins with the arrival of an action potential at the axon terminal(D), stimulating the movement of vesicles towards the membrane, which then fuse with the plasma membrane , releasing neurotransmitters into the synaptic cleft . These neurotransmitters bind to receptors on the postsynaptic neuron(A), opening ion channels that allow the entry of ions and can generate a new potential in the post-synaptic neuron. The new potential developed may be either excitatory or inhibitory. and generate a new potential (E).

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