Mark the given statements True (T) or False (F).

(i) A bacteriophage has 5386 nucleotides, bacteriophage lambda has 48502 bp, Escherichia coli has 4.6 × 10 6 bp and haploid content of human DNA is 3.3 × 10 9 bp.

(ii) Uracil nitrogenous base is present n RNA at the place of thymine.

(iii) A nitrogenous base is linked to the pentose sugar through a N-glycosidic linkage to form a nucleotide.

(iv) In nucleotide, a phosphate group is linked to 5’-OH of a nucleotide through phosphoester linkage.

(v) The backbone of polynucleotide chain is formed due to sugar and phosphate.

(vi) 5-methyl uracil is another chemical name for thymine.

(vii) Watson and Crick proposed Double Helix model for the structure of DNA based on the X-ray diffraction data produced by Wilkins and Franklin.

(viii) Adenine forms 2 hydrogen bonds with Thymine and Guanine forms 3 hydrogen bonds with cytosine.

(ix) The two chains of DNA are coiled in a left-handed fashion. The pitch of helix is 3.4 nm and there are roughly 10 bp in each turn.

(x) Francis Crick proposed the central dogma, which states that genetic information flows from DNA RNA protein.

(xi) In prokaryotes, DNA being negatively charged is held with some protein that have positively charges in a region termed as nucleoid.

(xii) In eukaryotes, DNA is held with set of positively charged, acidic proteins called histones. They are organized to form a unit of eight molecules called histone octamer.

(xiii) The DNA is wrapped around histone octamer to form structure called nucleosome. It contains 100 bp of DNA helix.

(xiv) Nucleosome constitute the repeating unit of a structure in nucleus called chromatin. They are seen as beads-on-string structure when viewed under electron microscope.

Choose the correct option given below: