Home Biology Biotechnology Principles and Processes If hemoglobin (Hb) of a normal individual an…
Biology Biotechnology Principles and Processes Single Correct MCQ
Published on: August 20, 2026

If hemoglobin (Hb) of a normal individual and a sickle-cell patient are run in electrophoretic field, they will show:-

A
same mobilities
B
different mobilities
C
Hb of patient will not move at all
D
Hbs are immobile

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Text Solution

Verified by Experts
The correct answer is:
B

Sickle-cell hemoglobin (HbS) differs from normal hemoglobin (HbA) due to a single amino acid substitution, which changes its net charge. Because electrophoresis separates molecules based on charge and size, HbA and HbS migrate differently in an electric field, so they show different mobilities.

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