Now a days it is possible to detect the mutated gene causin…

Biology Biotechnology and Its Application Previous Year Questions Single Correct MCQ

Published on: August 21, 2026

Now a days it is possible to detect the mutated gene causing cancer by allowing radioactive probe to hybridise its complimentary DNA in a clone of cells, followed by its detection using autoradiography because:

Mutated gene completely and clearly appears on a photographic film.

Mutated gene does not appear on a photographic film as the probe has no complimentarity with it.

Mutated gene does not appear on photographic film as the probe has complementarity with it.

Mutated gene partially appears on a photographic film.

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The correct answer is:

A single stranded DNA or RNA, tagged with a radioactive molecule (probe) is allowed to hybridize to its complementary DNA in a clone of cells followed by detection using autoradiography. The clone having the mutated gene will hence not appear on the photographic film, because the probe will not have complementarity with the mutated gene.

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