Which statement is incorrect ?
(I) Retroviruses have also been disarmed and are now used to deliver desirable genes into animals cells.
(II) Downstream processing is one of the steps of R-DNA technology.
(III) DNA is a negatively charged molecule.
(IV) The presence of chromogenic substrate gives blue colour colonies, if the plasmid in the bacteria does not have an insert.
Text Solution
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Statement (I - Correct): Scientists take dangerous animal viruses (retroviruses) and remove their harmful parts. They "disarm" them so they can safely carry good genes into animal cells.
Statement (II - Correct): After making a product using altered DNA, it must be cleaned and separated. This final cleanup step is called downstream processing.
Statement (III - Correct): DNA has chemical groups called phosphates. These phosphates carry a negative charge.
Statement (IV - Correct): Bacteria without a new gene insert can still make a special enzyme. This enzyme changes a test chemical into a blue colour, creating blue colonies.
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