Biology Biotechnology and Its Application Biotechnological Applications in Medicine Single Correct MCQ
Published on: August 11, 2026

For the first time, gene therapy was tried on a 4 year old girl in 1990 to treat which of the following enzyme deficiency?

A
Cytosine Deaminase (CDA)
B
Adenosine Deaminase (ADA)
C
Tyrosine oxidase
D
Glutamate dehydrogenase

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Text Solution

Verified by Experts
The correct answer is:
B

The first successful gene therapy was performed in 1990 on a 4-year-old girl suffering from Adenosine Deaminase (ADA) deficiency, which causes a severe immunodeficiency disease (SCID – Severe Combined Immunodeficiency). The normal ADA gene was introduced into her lymphocytes to restore immune function.

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