Production: Cyclosporin A is a cyclic non-ribosomal peptide metabolite produced through the fermentation of the filamentous fungus Trichoderma polysporum.

Function: It functions as a calcineurin inhibitor, which suppresses the activation of T-cells in the immune system.

Medical Use: It is critical in organ transplantation (kidney, liver, heart) to stop the body from attacking the newly grafted tissue.

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