Fill in the blanks and choose the correct option given below.

(I) Cancer causing agents are called ___A____ and cancer causing viruses are called ___B____ which have genes called ____C____.

(II) ____D____ or ____E_____ genes present in normal cells when activated under certain conditions lead to oncogenic transformation of cells.

(III) In treatment of cancer, patients are given substances called biological response modifier such as ___F___ which activates their immune system and helps in destroying tumor.

(IV) Heroin commonly called ____G____ is chemically ___H____ which is obtained from morphine by _____I____ reaction and is extracted from latex of poppy plant ____J_____ (Scientific name).

(V) Cannabinoids are obtained from the infloroscence of the plant ____K_____. They are known for their effects on ___L___ system of body.

(VI) Cocaine is obtained from coca plant ____M____ native to ____N____. It interferes with transport of neuro- transmitter ___O____.

(VII) Morphine is very effective ___P___ and _____Q____ and is very useful in patients who have undergone surgery.

(VIII) ___R____ is a chemical substance in tobacco that stimulates adrenal gland to release adrenaline and nor- adrenaline into blood.

(IX) Adolescence means both ___S____ and ____T____ during which a child becomes mature. The period between ____U_____ and ____V_____ years of age is adolescence period.

(X) Dependence is the tendency of the body to manifest a characteristic and unpleasant ____W_____ syndrome.

(XI) Excessive doses of drugs may lead to coma and death due to respiratory failure, heart failure or ___X____.

(XII) The chronic use of drugs and alcohol damages nervous system and ____Y_____.

(XIII) The damage to liver due to liver due to excessive use of drugs and alcohol is called ____Z_____.