Assertion: Eli Lilly prepared two DNA sequences of 
and 
chains of insulin and introduced them in the plasmids of one E.coli.
Reason: Chains A and B produced together by this E.coli is extracted and combined by creating disulfide bonds to form insulin.
Text Solution
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In 1983, Eli Lilly an American company prepared two DNA sequences corresponding to A and B, chains of human insulin and introduced them in plasmids of E. coli to produce insulin chains. Chains 
and 
were produced separately, extracted and combined by creating disulfide bonds to form human insulin.
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