DNA is a polymer of nucleotides which are linked to each other by 
phosphodiester bond. To prevent polymerisation of nucleotides, which of the following modifications would you choose?
Text Solution
Verified by ExpertsThe correct answer is:
B
DNA chain elongation requires the free 
on the sugar to form the 
phosphodiester bond with an incoming nucleotide's 5'-phosphate. If the 
is removed or modified, no phosphodiester bond can form, polymerisation stops. (Modifying the 
is irrelevant for DNA because deoxyribose already lacks a 
.)
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