The technique in which recombinant DNA directly injected into the nucleus of animals cell is called 
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The two physical methods for introducing DNA into the cells include use of microinjection or a gene gun (biolistics). In the former method, a very fine pipette is used to inject DNA molecules directly into nucleus of the animal cells to be transformed and in the latter, bombardment of cells is done with high velocity microprojectiles that are usually particles of gold or tungsten that have been coated with DNA.
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